活动

Epigenetic editing and therapeutic approaches to autism

Topic 

Epigenetic editing and therapeutic approaches to autism


Date and Time : 

22 November 2022, 10:00-11:00pm

Room A203-1, ZJE building 


Link:

Zoom:833 0831 3045

Passcode:aaaa1111


Speaker:

Prof. Rudolf Jaenisch

Founding Member, Whitehead Institute

Professor of Biology, MIT, Department of Biology


Host: Dr. Di Chen


Rudolf Jaenisch,美国科学院院士,麻省理工学院怀特黑德生物医学研究所教授,干细胞研究领域的权威人物,研究做出第一只转基因小鼠。他是怀特黑德研究所的创始人之一,曾经担任过国际干细胞学会的主席。其在一系列的领域做出了有影响的工作,包括基因敲除小鼠、表观遗传学研究、核移植、iPS等。


Jaenisch, a Whitehead Founding Member, focuses on understanding epigenetic regulation of gene expression. He is a pioneer in the study of cellular reprogramming, the process of converting adult cells into induced pluripotent stem (iPS) cells. 

 

Jaenisch’s lab was the first to create a transgenic animal model using SV40 and retroviruses. He has been the first to conduct an experiment showing that therapeutic cloning could correct genetic defects in mice. He is currently using patient-derived iPS cells to develop sophisticated models for the study of cancer, diabetes, and neurodegenerative disorders, including Alzheimer's disease and Parkinson's disease. Jaenisch is working with human stem cells to study disease risk factors. 

 

Jaenisch’s discoveries forever changed the landscape of how biological science is conducted. His methodological breakthroughs allow scientists, for the first time, to study human brain functions in normal and pathological conditions in its full complexity of all brain cell types. His stellar scientific acumen will be focused in partnership with Rick Young on condensate biology advancing research in cancer and neurodegenerative disease. 


Venue:

Zoom

Time:

1669125600000 - 1669129200000

Date:

1669125600000

Light sheet microscopy: push live imaging gently.

Light sheet microscopy: push live imaging gently.

Dr. Min Guo

College of Optical Science and Engineering, ZJU

Dr. Min Guo is a tenure-track professor (100-Talent Investigator) at Zhejiang University. He received his Ph.D. degree in Instrument and Meter Engineering at Zhejiang University in 2016. He joined the National Institutes of Health as a Postdoc Fellow in 2016 and then as a Biomedical Scientist in 2019 before he returned to Zhejiang University in 2022. His research interests focus on high temporal-spatial resolution fluorescence microscopy including structured illumination microscopy, light sheet microscopy, and microscopic image analysis. He has developed several cutting-edge imaging techniques adopted in biomedical research by more than 20 labs across the world, and published ~ 20 papers in Journals such as Nature, Nature Biotechnology, Nature Methods etc. He also won the NIBIB’s Xiuwen Wang Memorial Award in 2019 and the Microscopy Today Innovation Award in 2020.

 

Date and Time: 16 Nov. 2022, 15:30-16:30

Room A203-1, ZJE building

Host:Dr. James Wang


Venue:

ZJE大楼 A203

Time:

1668583800000 - 1668587400000

Date:

1668583800000

Circular RNAs: subtypes, functions, and related mechanisms

Circular RNAs: subtypes, functions, and related mechanisms.

Prof. Ge Shan

School of Basic Medicine, University of Science and Technology of China (In transition). Run -Run Shaw Hospital, School of Medicine, Zhejiang University


Prof. Ge Shan have been focused on the study of noncoding RNAs for their regulatory roles in the flow of genetic information. His lab has identified new noncoding RNAs (e.g. MecciRNAs, EIciRNA, 5S-OT, ASAT siRNA, tiny RNA, p53R175H Aptamer RNA), and have revealed functions and novel functional mechanisms of these ncRNAs. Shan lab have explored methodologies of utilizing noncoding RNAs (e.g. p53R175H Aptamer RNA and human 5S-OT) to modulate the expression of genetic information. Dr. Ge Shan have published research articles as the senior corresponding author in journals such as Developmental Cell, Nature Structural & Molecular Biology, PNAS, Science Advances, and Nature Communications. These studies have been highlighted in Nature Reviews Molecular Cell Biology, Nature Reviews Genetics, Nature Reviews Microbiology, Science Editors’ Choice, etc. Dr. Ge Shan is supported by grants and professorship to top young Chinese scientists such as “The National Science Fund for Distinguished Young Scholars” and the National Leading Scientist of the “Ten Thousand Talent Program”.

 

Date and Time: 9 Nov. 2022, 15:30-16:30

Room A203-1, ZJE building

Host:Dr. Lingfeng Meng


Venue:

ZJE大楼 A203-1

Time:

1667979000000 - 1667982600000

Date:

1667979000000

ACT系列讲座之校友说|关于海外留学,你想知道的都在这里

ACT系列讲座之校友说|关于海外留学,你想知道的都在这里

时间Time:19:00-21:00

日期 Date:2022-11-8

地点Venue:线上


WechatIMG2120.jpeg

Venue:

线上

Time:

1667905200000 - 1667912400000

Date:

1667905200000

How is evolutionary principle useful for biomedical research

Talk title:

How is evolutionary principle useful for biomedical research


Speaker Name and Position and Institute:

Guojie Zhang 

Chair Professor, Evolutionary & Organismal Biology Research Center, School of Medicine, Zhejiang University

Adjunct Professor in University of Copenhagen and Kunming Institute of Zoology

Speaker introduction or talk content:

Professor Guojie Zhang is an expert in biodiversity genomics and ecological evolutionary genomics. He is currently a chair professor at Evolutionary & Organismal Biology Research Center of Zhejiang University, and an adjunct professor at the University of Copenhagen and the Kunming Institute of Zoology, Chinese Academy of Sciences. Before he joined Zhejiang University, he was also the youngest full professor at the University of Copenhagen. 

Professor Guojie Zhang has made outstanding academic contributions in the frontier field of biodiversity genomics and ecological evolutionary genomics. As of August 2019, more than 120 papers have been published in international high-impact academic journals, including 14 articles in Science, 8 articles in Nature, 6 articles in Nature Genetics, 1 article in Cell, and dozens of Nature research journals. He has successively served as a judge for many national foundations such as the United States, Canada, France, Switzerland, the United Kingdom, Denmark, Sweden, Israel, etc., and has served as a manuscript reviewer for many top international journals including Nature, Science, and Cell. He is also as editorial Board member of GigaScience, Human Heredity, Zoological Research and the Encyclopedia of Life Sciences.


Host:

Prof. Suhong Xu

Date:

2022/11/3 Thursday, 3:30pm-4:30pm


Venue:

ZJE大楼A203-1

Time:

1667460600000 - 1667464200000

Date:

1667460600000

The late stage of autophagy

The late stage of autophagy

Prof. Yueguang Rong

School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology

In 2012, Prof. Yueguang Rong got his PhD training from Tsinghua University in Dr. Li Yu’s lab, and then did his postdoctoral research at UT Southwestern Medical Center in America with Dr. Qing Zhong (2012-2017). He moved back to Huazhong University of Science and Technology, and was appointed as the director of pathology department in 2018. He was supported by Overseas High-level Young Talents Project, the Major Research Plan and General Program of NSFC. His research works was published in Nature Cell Biology, Journal of Cell Biology, PNAS, Trends Cell Biology and Autophagy. His primary research interests focus on the late stage of autophagy including autophagic lysosome reformation (ALR), autophagosomal components recycling (ACR) and autophagosome-lysosome fusion and the related physiological/pathological functions. He dissected the spinster, clathrin and PI (4,5) P2 related mechanism for autophagic lysosome reformation (ALR). Recently, he discovered a novel cellular process and identified the ‘RECYCLER’ complex for ACR. 

 

Date and Time: 26 Oct. 2022, 15:30-16:30

Room A203-1, ZJE building

Host:Dr. Zhi Hong


Venue:

ZJE大楼 A203-1

Time:

1666769400000 - 1666773000000

Date:

1666769400000

Germinal center selection and neuronal regulation of humoral immunity

Germinal center selection and neuronal regulation of humoral immunity

Prof. Hai Qi

Dean of School of Medicine Laboratory of Dynamic Immunobiology, Institute for Immunology Tsinghua University


Dr. Qi is a Professor in Immunology at Tsinghua University. He studies humoral immune regulation and germinal center biology. His work has made important contributions to our understanding of molecular mechanisms underlying T-B interactions, follicular helper T-cell development and function, and germinal center positive selection. His group has also made important advances in mechanistic understanding of how sexual dimorphism is orchestrated in B-cell immunity and how brain can directly control antibody responses. Dr. Qi is an HHMI International Scholar and has been recognized by numerous awards, including an AAI-BD Investigator Award.

 

Date and Time: 25 Oct.(Monday) 2022, 15:30-16:30

Room A203-1, ZJE building

Host: Prof. Wanlu Liu


Venue:

ZJE大楼 A203-1

Time:

1666683000000 - 1666686600000

Date:

1666683000000

Systems Virology and Immunology

Systems Virology and Immunology

Prof. Ren Sun

Chair professor and Director of Center for Infectious Disease Research.

School of Life Sciences, Westlake University.

Professor Ren Sun takes systems biology approaches to address critical interactions between virus and host. His lab has integrated genomics, proteomics, structural biology to characterize biological processes at both population and single virus/cell levels. His team has developed a method that can generate functional maps of entire viral genomes at single nucleotide resolution. It lays the foundation for comprehensively defining virus-host interactions, and enables engineering virus for rational vaccine design. The approach was demonstrated with influenza virus in vitro and in vivo: when the immune-evasion functions were systematically identified and removed from the viral genome, the engineered viruses became more immunogenic than the wild type, but severely attenuated in vivo. Thereby, it can be a general rational approach to develop therapeutic or prophylactic vaccine for many pathogens. His team is also developing high-throughput technology platforms to map epitope-specific antibody responses, to systematically define the immunome of hosts post infection or vaccination. These technology platforms will be also applied to studies on allergy, auto-immune diseases and neuroimmunology.

 

Date and Time: 12 Oct. 2022, 15:30-16:30

Room A203-1, ZJE building

Host:Dr. Liu Wanlu


Venue:

ZJE大楼,A203-1

Time:

1665559800000 - 1665563400000

Date:

1665559800000

Exploration of clinical application of biomaterials

Exploration of clinical application of biomaterials

Prof. Min ZHOU

Doctoral supervisor

Institute of Translational Medicine, Zhejiang University

Prof. Zhou is an outstanding scientist focusing on novel biomaterial development and the clinical application of biomedical materials. He has carried out in-depth and systematic research on the early diagnosis and precise treatment of major diseases such as malignant tumors and infectious diseases, and has achieved a series of innovative findings. He has published more than 100 papers in high-impact journals such as Nature Communications, Science Advances, and Advanced Materials, including 10 cover papers. The nanodrug developed in his group has been used in clinical trials, which has successfully cured many patients. In 2017 and 2018, Prof. Zhou won the "Top Ten Annual Academic Progress Nomination Award of Zhejiang University". His achievements have been widely reported by the media, such as Xinhua News Agency, People's Network, Guangming Network, Zhejiang Daily, Zhejiang Satellite TV and so on. His invention was considered as one of new technologies recommended in the drug delivery field in the Nature Medicine magazine.

 

Date and Time: 11 Oct. 2022, 14:00-14:50

Room A203-1, ZJE building

Host:Dr. Yuehai KE


Venue:

ZJE大楼 A203-1

Time:

1665468000000 - 1665471000000

Date:

1665468000000

Systems Virology and Immunology

Systems Virology and Immunology

Prof. Ren Sun

Chair professor and Director of Center for Infectious Disease Research.

School of Life Sciences, Westlake University.

Professor Ren Sun takes systems biology approaches to address critical interactions between virus and host. His lab has integrated genomics, proteomics, structural biology to characterize biological processes at both population and single virus/cell levels. His team has developed a method that can generate functional maps of entire viral genomes at single nucleotide resolution. It lays the foundation for comprehensively defining virus-host interactions, and enables engineering virus for rational vaccine design. The approach was demonstrated with influenza virus in vitro and in vivo: when the immune-evasion functions were systematically identified and removed from the viral genome, the engineered viruses became more immunogenic than the wild type, but severely attenuated in vivo. Thereby, it can be a general rational approach to develop therapeutic or prophylactic vaccine for many pathogens. His team is also developing high-throughput technology platforms to map epitope-specific antibody responses, to systematically define the immunome of hosts post infection or vaccination. These technology platforms will be also applied to studies on allergy, auto-immune diseases and neuroimmunology.

 

Date and Time: 12 Oct. 2022, 15:30-16:30

Room A203-1, ZJE building

Host:Dr. Liu Wanlu


Venue:

ZJE大楼 A203-1

Time:

1665559800000 - 1665563400000

Date:

1665559800000

The axolotl’s journey to the modern molecular era

The axolotl’s journey to the modern molecular era

Prof. JiFeng Fei

Doctoral supervisor

Guangdong Provincial People’s Hospital/ Guangdong Academy of Medical Sciences


Prof. JiFeng Fei is a Guangdong Pearl River Scholar Distinguished Professor, member of the Youth Committee and Developmental Biology Committee of the Chinese Society for Cell Biology. He has long been engaged in using animal organisms to generate disease models to study the mechanisms of central nervous system development and regeneration. In recent years, he mainly focused on a vertebrate model Mexican axolotls to elucidate its molecular and cellular mechanisms of tissue regeneration using functional genomics, single-cell sequencing, spatial transcriptomics, living-imaging and drug screening approaches, which may provide feasible strategies to improve limited regenerative capacity in mammals. He has published more than 20 research articles in peer reviewed journals, including Nature, Science, Nature Commun, Nature Protoc, PNAS, PLoS Biol and Cell Rep.

 

Date and Time: 28 Sept. 2022, 15:30-16:30

Room A203-1, ZJE building

Host:Dr. Wang Chaochen


Venue:

ZJE大楼 A203

Time:

1664350200000 - 1664353800000

Date:

1664350200000

Venue:

Online

Time:

1664249400000 - 1664253000000

Date:

1664249400000

Venue:

圆正酒店

Time:

1663579800000 - 1663585200000

Date:

1663579800000

Venue:

Time:

1662858000000 - 1662865200000

Date:

1662858000000

2022级新生报道

欢迎2022级新生们加入国际校区

Venue:

浙大国际校区

Time:

1661126400000 - 1661680800000

Date:

1661126400000

2022届毕业生晚会

欢迎老师同学们参与2022届毕业生晚会

祝福毕业生们毕业快乐前程似锦!

Venue:

多功能厅

Time:

1655980200000 - 1655985600000

Date:

1655980200000

Venue:

东讲堂 102

Time:

1655438400000 - 1655442000000

Date:

1655438400000

Host-microbial interactions and lipid metabolism

Talk title:Host-microbial interactions and lipid metabolism

 

Yuhao Wang

PI , Doctoral supervisor

Institute of Translational Medicine, School of Medicine, ZJU

Introduction:Dr. Yuhao Wang received his Ph.D degree and completed his postdoctoral research from the University of Texas Southwestern Medical Center at Dallas. In 2020, he was named National High-level Young Scholar and Zhejiang University “Hundred Talents Program” Scholar. In the same year, he started his own group in the Institute of Translational Medicine at Zhejiang University School of Medicine. Dr. Wang’s research interest is to explore the interactions between host and intestinal microbiota, especially focusing on understanding of the molecular mechanisms by which the microbiota regulates host lipid metabolism. His research achievements include the finding of microbiota regulation of lipid metabolism through the circadian clock machinery, and the discovery of transcription factor NFIL3 as an essential host factor by which connects the microbiota and metabolism, etc. These findings were published in scientific journals such as Science, PNAS and eLife. One of these publications was awarded as “Top Gut Microbiota Paper of The Year” by the American Gastroenterological Association.

 


Date and Time : 26 May 2022, 15:30-16:30

Room A203-1, ZJE building

Host:Dr. Wang Chaochen


Venue:

ZJE大楼 A203

Time:

1653550200000 - 1653553800000

Date:

1653550200000

Venue:

Online

Time:

1653393600000 - 1653397200000

Date:

1653393600000

Venue:

Zoom Online

Time:

1652155200000 - 1652162400000

Date:

1652155200000

Venue:

Teams Online

Time:

1651131000000 - 1651135500000

Date:

1651131000000

Venue:

ZJE大楼 A203

Time:

1651204800000 - 1651208400000

Date:

1651204800000

ZJE Faculty Meeting

The agenda proposed as follows:

-welcome acting dean Prof. Guo and congratulation to Prof. Suhong as vice dean

-welcome new arriving staff

-pandemic control in Haining

-teaching activity (UG programme progress)

-progress of PG (dual degree and UoE single degree student recruitment)

-progress of research (funding and core facility)


Venue:

Online

Time:

1650999600000 - 1651003200000

Date:

1650999600000

Venue:

腾讯会议

Time:

1650870000000 - 1650877200000

Date:

1650870000000

Venue:

ZJE大楼 A203

Time:

1650600000000 - 1650603600000

Date:

1650600000000