On November 19th, 2025, the 142nd Biomed-X Research Seminar of the ZJE was successfully held in the Room 2A-203, ZJE Building. At the invitation of Dr. James Qun Wang from the Centre for Cellular Biology and Signalling (CBS) of ZJE, Prof. JIANG Hong from Sichuan University delivered an academic report titled "Focal adhesion kinase in pancreatic cancer: from cell motility control to immunomodulation and beyond".
Professor JIANG Hong's report focused on the multiple roles of Focal Adhesion Kinase (FAK) in pancreatic cancer, systematically elaborating on the research context of this kinase from its classical functions to innovative mechanisms. On one hand, it focused on the core role of FAK in regulating the motility of pancreatic cancer cells, revealing the molecular mechanism by which FAK affects tumor cell migration and invasion through mediating cell adhesion and cytoskeletal remodeling. On the other hand, it extended to the field of tumor immunomodulation, deeply analyzing how FAK participates in the remodeling of the tumor immune microenvironment and regulates immune cell functions as well as the formation of immunosuppressive networks. Meanwhile, the report also involved the extended exploration of this research in translational medicine, providing theoretical support and potential directions for the combined strategy of targeted therapy and immunotherapy for pancreatic cancer.
During the event, faculty and students interacted actively, fully demonstrating the academic atmosphere of free discussion and critical thinking in the institute. Professor JIANG carefully and meticulously answered every question, enabling teachers and students to gain a deeper understanding of the cutting-edge progress, innovative directions and translational prospects in this field.
As the 142nd session of the Biomed-X Seminar series, this report underscores the institute's commitment to fostering high-level academic exchanges through its academic brand building efforts. The institute will continue to provide a platform for faculty and students to engage in cutting-edge scientific discussions.
