The Centre for Infection Immunity and Cancer CIIC is a disease-oriented centre that will apply experimental medicine for human disease to facilitate bench-to-bedside medicine. The centre will focus on health and disease across the whole human body applying investigations of systemic diseases, multi-tissue models and multi-omits for the disease related Cancer & Immunity. The centre will investigate organ-specific diseases (across the whole human), the systemic links between organs and how immune cross-talk correlates to pathophysiology in the hope of alleviating both infection and disease. The centre will use pre-clinical models with an immune & cancer focus and develop models with broad applications across ZJE and various university and clinical partners. There will be a strong focus on comparative biology, spatial genomics and multi-omics coupled to development of computational tools for systemic comparisons. Models will including in vivo animal models of lung cancer & immunity, in vivo lentivirus intranasal/intra-oral delivery and immuno-stimulatory PRR mouse models for inflammation. The centre will develop stronger links with the core animal facility in the development of these models and offer them for collaborators (service-based).
ZJE: Aaron Irving, Jian Liu, James Wang, Sue Welburn, Yuehai Ke, Hugo Samano, Dmytro Shytikov
Affiliated: Linrong Lu, Xin Xie, Chaochen Wang, Kuan Yoow Chan, Wei Guo, Zhaoyuan Fang, Stijn van Der Veen, Wanlu Liu, Richard Sloan, Jürgen Haas, Till Bachmann, Vasso Makrantoni
Partners: SAHZU, UoE and ZJU Medical Schools
职占位称 : Centre for Infection Immunity and Cancer (IIC)
邮占位箱 : Aaron Irving & Jian Liu
研究方向 : The Centre for Infection Immunity and Cancer CIIC is a disease-oriented centre that will apply experimental medicine for human disease to facilitate bench-to-bedside medicine. The centre will focus on health and disease across the whole human body applying investigations of systemic diseases, multi-tissue models and multi-omits for the disease related Cancer & Immunity. The centre will investigate organ-specific diseases (across the whole human), the systemic links between organs and how immune cross-talk correlates to pathophysiology in the hope of alleviating both infection and disease. The centre will use pre-clinical models with an immune & cancer focus and develop models with broad applications across ZJE and various university and clinical partners. There will be a strong focus on comparative biology, spatial genomics and multi-omics coupled to development of computational tools for systemic comparisons. Models will including in vivo animal models of lung cancer & immunity, in vivo lentivirus intranasal/intra-oral delivery and immuno-stimulatory PRR mouse models for inflammation. The centre will develop stronger links with the core animal facility in the development of these models and offer them for collaborators (service-based). ZJE: Aaron Irving, Jian Liu, James Wang, Sue Welburn, Yuehai Ke, Hugo Samano, Dmytro ShytikovAffiliated: Linrong Lu, Xin Xie, Chaochen Wang, Kuan Yoow Chan, Wei Guo, Zhaoyuan Fang, Stijn van Der Veen, Wanlu Liu, Richard Sloan, Jürgen Haas, Till Bachmann, Vasso MakrantoniPartners: SAHZU, UoE and ZJU Medical Schools
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